Follow up lumbar puncture, days after diagnosis, reduces death from cryptococcal meningitis in AIDS

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High opening pressure at lumbar puncture (LP) (spinal tap) is recognised as a poor prognostic feature of cryptococcal meningitis. For these patients repeated LP is advocated, including the use of lumbar drains or ventricular shunts in some cases. In a provocative paper from Uganda, Rolfes and colleagues found that at least one ‘therapeutic’ LP for… Read more »