OUR VISION IS TO REDUCE ILLNESS AND DEATH ASSOCIATED WITH FUNGAL DISEASES WORLDWIDE.

News

Keep up to date with the latest news items from GAFFI.

Burden of fungal diseases in Turkey, Norway, Malawi and Argentina presented at TIMM, Belgrade

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Estimates of the number of serious fungal infections in Turkey,  (population 79.8M), Norway (5.2M), Malawi (17.7M), Argentina (43.6M) were presented today in Belgrade at the Trends in Medical Mycology (TIMM) meeting. Fungal asthma was especially common in Argentina and Norway (606 and 340/100,000) and fewer cases in Turkey at 87.3/100,000, although there is likely some… Read more »

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Already saving lives from fungal disease – GAFFI’s 4-year legacy

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The Global Action Fund for Fungal infections, GAFFI, (www.gaffi.org)  has been operational for 4 years and among its many successes, none is more important or indicative of its work, than directly saving lives in Guatemala. This program of implementing well known diagnostic tests in a reference laboratory, has picked up 139 life-threatening fungal infections in… Read more »

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Professor Matthew Burton of the London School of Hygiene & Tropical Medicine appointed as a GAFFI Senior Adviser

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One of GAFFI’s priority diseases is fungal (mycotic) keratitis, which leaves 100,000’s blind in at least one eye each year. Professor Matthew Burton is a Wellcome Trust funded clinical researcher focused on corneal infection. He brings deep expertise in to GAFFI in microbial keratitis, with years of experience in Africa and many international collaborations. Matthew… Read more »

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Call for global action on life-threatening fungal infections

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University of Manchester researchers have co-ordinated a ‘first of its kind’ series, published today in the prestigious journal The Lancet Infectious Diseases.The series of papers gives new insights into the breadth of fungal diseases and a call to action for world health bodies to prevent millions of infections each year. Killing over 1.5 million and… Read more »

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Major clinical trial shows flucytosine a critical component of reducing deaths from cryptococcal meningitis

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At the International AIDS Society conference in Paris today, Sile Molloy from St George’s Hospital Medical School in London presented the ACTA study results: the largest ever study of cryptococcal meningitis. 678 evaluable patients from 9 sites in 4 African countries were randomized into an all oral regimen of fluconazole (1200mg/d) and flycytosine (100mg/d), amphotericin… Read more »

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Randomised trial establishes amphotericin B as best immediate therapy for Talaromyces marneffei infection in AIDS

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In a 440 patients study in Vietnam, Dr Thuy Le and colleagues show that conventional amphotericin B is superior to itraconazole for the treatment of talaromycosis in AIDS. Their paper published this month in the New England Journal of Medicine, finds not difference in 2 week mortality (6,2%), but a substantially higher mortality at 24… Read more »

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POOR FARMER’S FUNGAL SKIN CONDITION GETS APPROVAL FROM WHO AS ‘NEGLECTED’ AFTER LOBBYING BY GAFFI

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GAFFI (Global Action For Fungal Infection) today welcomes news from the World Health Organisation (WHO) that it has classed the disease known as chromoblastomycosis – a disfiguring fungal disease of poor farmers in South America, Africa, and Asia – as a neglected tropical disease (NTD). Chromoblastomycosis also known as chromomycosis, is one of the most… Read more »

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FUNGAL MENINGITIS STILL KILLING OVER 180,000 PEOPLE EACH YEAR DESPITE DRUGS AVAILABLE TO SAVE LIVES

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International HIV experts on fungal meningitis in AIDS report finding nearly 250,000 cases annually, 73% in sub-Saharan Africa. Fungal meningitis due to the Cryptococcus fungus typically affects those in the prime of life, 35 years old, and affects the tissues covering the brain and spinal cord. Of those affected an estimated 181,000 people die, despite… Read more »

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Burden of fungal diseases in Belarus, Cameroon, Indonesia and Italy presented at ECCMID Vienna

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For the fourth year running, multiple country burdens of fungal diseases have been presented at ECCMID; 4 countries covering a population of 351 million people. The remarkable findings were: The annual incidence of candidaemia in Italy is 24/100,000 and was estimated at 5/100,000 for Belarus, Cameroon and Indonesia, in the absence of data. Cryptococcal meningitis… Read more »

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Ruling by World Health Organisation delights Doctors

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Itraconazole, voriconazole and natamycin 5% ophthalmic preparation ruled as ‘essential antifungals’  GAFFI (Global Action Fund for Fungal Infections) says today’s announcement that three drugs capable of reducing deaths in hundreds of thousands of people worldwide have been given essential medicines status is a Red Letter Day in the fight to reduce blindness and save lives…. Read more »

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